DR. MIKE POSTHUMUS


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Position

·         Postdoctoral Research Fellow, UCT/MRC Research Unit for Exercise Science and Sports Medicine (ESSM), Department of Human Biology, Faculty of Health Sciences, University of Cape Town

 

 Qualifications

  • PhD (Physiology), University of Cape Town (2009)

    Thesis title:The Genetics of Anterior Cruciate Ligament Ruptures

  • BSc(Med)(Hons) Exercise Science, The University of Cape Town, 2005

  • BSc, The University of Cape Town, 2004

 

ESSM research groups

  • Injuries and medical conditions associated with sport and exercise

 

RESEARCH INTERESTS

  • The biology of musculoskeletal soft tissue.

  • The genetic contribution to musculoskeletal soft tissue injuries.

  • The genetics of sports performance.

  • Treatment modalities in musculoskeletal soft tissue injuries.

 

CONTACT

Tel:      +27 21 650 4567

Email:  mposthumus@me.com

 

PUBLICATIONS

1.        Brown, J. Miller, CJ. Posthumus, M. Schwellnus, MP. Collins, M. The COL5A1 gene, ultra-marathon running performance and range of motion. International Journal of Sports Physiology and Performance. In Press

2.        Posthumus, M. Collins, M. September, AV. Schwellnus, MP. The intrinsic risk factors for ACL ruptures: An evidence-based review. The Physician and Sportsmedicine. In Press.

3.        Posthumus, M. Collins, M. van der Merwe, L. O’Cuinneagain, D. van der Merwe, W. Ribbans, W.J. Schwellnus, MP. Raleigh, SM. Matrix metalloproteinase genes on chromosome 11q22 and the risk of anterior cruciate ligament (ACL) rupture. Scandinavian Journal of Science and Medicine in Sports. In Press.

4.        Posthumus, M. Schwellnus, M. Collins, M. The COL5A1 gene: a novel marker of endurance running performance. Medicine & Science in Sports & Exercise. In Press.

5.        Posthumus, M. September, AV. Schwellnus, M. Collins, M. The COL5A1 gene and musculoskeletal soft tissue injuries. The South African Journal of Sports Medicine, 2010. 22(2):38-41.

6.        Posthumus, M. September, AV. Schwellnus, MP. Collins, M. Identification of genetic risk factors underlying complex multifactorial phenotypes. Knee Surgery, Sports Traumatology, Arthroscopy, 2010. 18(12):1810-11.

7.        Posthumus, M. Raleigh, SM. Ribbans, WJ. Schwellnus, MP. Collins, M. A functional variant within the MMP3 gene does not associate with human range of motion. Journal of Science and Medicine in Sport, 2010. 13(6):630-2.

8.        Posthumus, M. Collins M. Cook, J. Handley, CJ. Ribbans, WJ. Smith, RKW. Schwellnus, MP. Raleigh, SM. Components of the transforming growth factor-B family and the pathogenesis of human Achilles tendon pathology – a genetic association study. Rheumatology, 2010. 49(11):2090-7.

9.        Posthumus, M. September, AV. O’Cuinneagain, D. van der Merwe, W. Schwellnus, MP. Collins, M. The COL12A1 gene and risk of anterior cruciate ligament ruptures. British Journal of Sports Medicine, In Press.

10.     Posthumus, M. September, AV. O’Cuinneagain, D. van der Merwe, W. Schwellnus, MP. Collins, M. The COL5A1 gene in associated with increased risk of anterior cruciate ligament ruptures in female participants. American Journal of Sports Medicine, 2009. 37(11):2234-40.

11.     Collins, M. Posthumus, M. Schwellnus, MP. The COL1A1 gene and acute soft tissue ruptures. British Journal of Sport Medicine, 2010. 44(4):1063-4.

12.     Posthumus, M. September, AV. Keegan, M. O’Cuinneagain, D. van der Merwe, W. Schwellnus, MP. Collins, M. Genetic risk factors for anterior cruciate ligament ruptures: The COL1A1 gene variant. British Journal of Sport Medicine, 2009. 43:352-356.

13.     Posthumus, M, September, AV. Schwellnus, MP. Collins, M. Investigation of the Sp1-binding site polymorphism within the COL1A1 gene in participants with Achilles tendon injuries and controls. Journal of Science and Medicine in Sport, 2009. 12:184-189.

14.     Posthumus, M. Viljoen, W. BokSmart: Safe and effective technique in Rugby union. The South African Journal of Sports Medicine, 2008. 20(3):64-70.

15.     September, AV. Posthumus, M. van der Merwe, L. Schwellnus, MP. Noakes, TD. Collins, M. (2008) The COL12A1 and COL14A1 genes and Achilles tendon injuries.  International Journal of Sports Medicine, 2008. 29:257-263.

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