DR. JULIA GOEDECKE

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POSITION

  • Specialist Scientist for the South African Medical Research Council

  • Honorary senior lecturer, UCT/MRC Research Unit for Exercise Science and Sports Medicine (ESSM), Department of Human Biology, Faculty of Health Sciences, University of Cape Town

 

QUALIFICATIONS

  • PhD (Physiology) (Exercise Science), University of Cape Town (2000)

    Thesis title: Fat as a fuel for exercise

  • BSc (Med)(Hons) (Nutrition and Dietetics), University of Cape Town (1994)

  • BSc (Physiology) University of Cape Town, (1992)

 

ESSM RESEARCH GROUPS

  • Exercise in the management of chronic disease

  • Exercise performance

 

RESEARCH INTEREST

  • Ethnic differences in obesity and the manifestation of the metabolic syndrome in South African women, exploring the mechanisms underlying this association, in particular examining the role of the adipose tissue depots. This is currently being examined at a physiological and molecular level, as well as incorporating interactions with diet, physical activity, and socio-cultural factors. 

  • Individual variability in substrate metabolism with special reference to obesity, as well as exercise performance. This research also explores the regulation of fat and carbohydrate metabolism at rest and during exercise.

 

CONTACT

 

Tel:      +27 21 650 4573

Email:  Julia.Goedecke@uct.ac.za

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PUBLICATIONS

1.   Goedecke JH, Utzschneider K, Faulenbach MV, Rizzo M, Berneis K, Spinas GA, Dave JA, Levitt DS, Lambert EV, Olsson T, Kahn SE. Ethnic differences in serum lipoproteins and their determinants in South African women. Metabolism (in press)

2.   Alvehus M, Burén J, Sjöström M; Goedecke JH, Olsson T.  The human adipose tissue depots have unique inflammatory patterns. Obesity (in press)

3.   Berneis K, Rizzo M, Evans J, Rini GB, Spinas GA, Goedecke JH. Interleukin-18 levels are associated with low-density lipoproteins size. Eur J Clin Invest. 2010 40(1):54-5, 2010.

4.   Jennings CL, Micklesfield LK, Lambert MI, Lambert EV, Collins M, Goedecke JH. Comparison of body fatness measurements by near-infrared reactance and dual-energy X-ray absorptiometry in normal-weight and obese black and white women. Br J Nutr. 2009 Nov 2:1-5. [Epub ahead of print]

5.   Goedecke JH, Rae DE, Smuts M, Lambert EV, O’Shea M. CLA supplementation in regularly exercising individuals: Incorporation of the t10c12 and c9t11 CLA isomers into human adipose tissue and skeletal muscle. Lipids 4(11):983-988, 2009

6.   Micklesfield LK, Evans J, Norris SA, Lambert EV, Jennings C, Joffe Y, Levitt NS, Goedecke JH.  Dual energy x-ray absorptiometry and anthropometric estimates of visceral fat in black and white South African women. Obesity Sep 17, 2009 [epub ahead of print]

7.   Goedecke JH, Dave JA, Faulenbach MV, Utzschneider KM, Lambert EV, West S, Collins M, Olsson T, Walker BR; Seckl JR, Kahn SE, Levitt NS. Insulin response in relation to insulin sensitivity: An appropriate b-response in black South African women. Diabetes Care 32(5):860-5, 2009

8.   Goedecke JH, Levitt NS, Lambert EV, Utzschneider KM, Faulenbach MV, Dave J, West S, Victor H, Evans J, Olsson T, Walker BR, Seckl JR, Kahn SE. Differential effects of abdominal Adipose tissue Distribution on insulin sensitivity in black and white South African women. Obesity 17(8): 1506-12, 2009

9.   Berman P, Collins M, Baumgarten I, Seoighe C, Jennings C, Joffe Y; Lambert EV, Levitt NS, Faulenbach MV, Kahn SE, Goedecke JH. Association between the 4 bp proinsulin gene insertion polymorphism (INS-69) and body composition in black African women. Obesity 17(6):1298-300, 2009

10.  Jennings CL, Lambert EV, Collins M, Levitt N, Goedecke JH.  Atypical presentation of the metabolic syndrome components in black African women; the influence of regional adipose tissue distribution. Metabolism 58: 149-157, 2009

11.  Havemann L and Goedecke JH. Nutritional practises of male cyclists before and during an ultra-endurance event. Int J Sports Nutr Exerc Metab 18:1-18, 2008

12.  Magnusson B, Gummesson A, Glad CAM, Goedecke JH, Jernås M, Lystig TC, Carlsson B, Fagerberg B, Carlsson LMS Svensson P-A. Cell death–inducing DFF45-like effector C is reduced by caloric restriction and regulates adipocyte lipid metabolism. Metabolism Clinical and Experimental 57: 1307–1313, 2008

13.  Dugas LR, Cohen R, Carstens MT, Schoffelen PM, Luke A, Goedecke JH, Levitt NS, Lambert EV.  Total daily energy expenditure in black and white, lean and obese South African women. Eur J Clin Nutr 63(5): 667-73, 2008

14.  Jennings CL, Lambert EV, Collins M, Joffe Y, Levitt N, Goedecke JH.  Determinants of a healthy metabolic phenotype in normal weight and obese black South African women.  Obesity 16:1602-1609, 2008

15.  Mciza Z, Goedecke JH, Lambert EV. Validity and reliability of a physical activity/inactivity questionnaire in South African primary school girls. SAJSM 19(4):80-87, 2007

16.  Micklesfield L, Reid S, Bewerunge L, Rush EC, Goedecke JH. A proposed method to measure body composition in obese individuals using dual energy X-ray absorptiometry. Int Journal Body Comp Research 5(4):147-151, 2007

17.  Evans JP, Collins M, Jennings CL, van der Merwe L, Söderström I, Olsson T, Levitt NS, Lambert   EV, Goedecke JH. IL-18 genotype and serum levels are associated with metabolic risk factors for cardiovascular disease.  Eur J Endocrinol 157(5): 633-40, 2007

18.  Joubert J, Norman R, Bradshaw D, Goedecke JH, Steyn NP, Puoane T and the South African Comparative Risk Assessment Collaborating Group.  Estimating the burden of disease attributable to excess body weight in South Africa in 2000. S Afr Med J 97: 683-690, 2007

19.  Rush EC, Goedecke JH, Jennings C, Micklesfield L, Dugas L, Lambert EV, Plank L.  BMI, fat and muscle differences in Urban Women of five ethnicities from two countries. Int J Obes 31(8):1232-9, 2007

20.  Lambert EV, Goedecke JH, Bluett K, Heggie K, Claassen A, Hudson D, West S, Dugas J, Keytel L, Meltzer S, Charlton K, Mohede I.  CLA: Effects on body composition, appetite and insulin sensitivity in trained persons.  Br J Nutrition 97:1001-1011, 2007

21.  Goedecke JH, Wake DJ, Levitt NS, Lambert EV, Collins M, Morton NM, Andrew R, Seckl JR, Walker BR. Glucocorticoid metabolism within superficial subcutaneous rather than visceral adipose tissue is associated with features of the metabolic syndrome in South African women. Clin Endocrinol 65(1):81-7, 2006

22.  West S, Goedecke JH, van Niekerk L, Collins M, St. Clair Gibson A, Macdonald I, Noakes TD, Lambert EV.  Adrenaline infusion: Effects on substrate metabolism, muscle recruitment and effort perception during low-to-moderate intensity exercise.  Pflugers Archives 451(6):727-737, 2006

23.  Havemann L, West S, Goedecke JH, Macdonald IA, Noakes TD, Lambert EV.  Fat adaptation followed by carbohydrate loading compromises high-intensity sprint performance.  J Appl Physiol 100(1): 194-202, 2006

24.  Mciza Z, Goedecke JH, Steyn NP, Charlton K, Puoane T, Meltzer S, Levitt NS, Lambert EV.  Development and validation of instruments measuring body image and body weight dissatisfaction in South African mothers and their daughters.  Public Health Nutrition 8(5):509-519, 2005

25.  St Clair Gibson A, Goedecke JH, Harley YX, Myers LJ, Lambert MI, Lambert EV.  Metabolic setpoint control mechanisms in different physiological systems at rest and during exercise. J Theor Biol 236:60-72, 2005

26.  Keytel LR, Goedecke JH, Noakes TN, Hiiloskorpi H, Laukkanen R, Van Der Merwe L, Lambert EV.  Prediction of energy expenditure from heart rate monitoring during submaximal exercise.  J Sports Sciences 23(3):289-297, 2005

27.  Goedecke JH; Clark VR, Noakes TD, Lambert EV.  The effects of medium-chain triacylglycerol and carbohydrate ingestion on ultra-endurance exercise performance.  Int J Sport Nutr Exerc Metabolism 14:15-27, 2005

28.  Sharwood KA, Collins M, Goedecke JH, Wilson G, Noakes TD.  Weight changes, medical complications and performance during an Ironman Triathlon.  Br J Sport Med 38:718-724, 2004

29.  Goedecke JH, Lambert EV.  Adaptation to a high-fat diet for endurance exercise: review of potential underlying mechanisms.  Int SportMed J 4 (6), 2003.  URL: http://www.esportmed.com.

30.  Goedecke JH, Barsdorf M, Beglinger C, Levitt NS, Lambert EV. Effects of a lipase inhibitor (Orlistat) on cholecytokinin and appetite in response to a high-fat meal. Int J Obesity Relat Metab Disord 27 (12): 1479-1485, 2003

31.  Lambert EV, Goedecke JH.  The role of dietary macronutrients for optimising endurance performance.  Curr Sports Med Rep 2(4): 194-201, 2003

32.  Lambert EV and Goedecke JH. Energy balance and energy expenditure in obesity: is obesity a disease of inactivity? South African Sports Med J 15 (1):21-25, 2003

33.  Sharwood K, Collins M, Goedecke J, Wilson G, Noakes T. Weight changes, sodium levels, and performance in the South African Ironman Triathlon. Clin J Sport Med 12(6): 391-399, 2002

34.  Goedecke JH, Levitt, N, St Clair Gibson A, Grobler L, Noakes TD, Lambert EV. Insulin sensitivity measured by the Minimal Model: Associations with fasting respiratory exchange ratio in trained athletes. Metabolism 50(11):1286-1292, 2001

35.  Goedecke JH, Claassen A, Noakes TD, Lambert EV. Fasting respiratory exchange ratio measured at rest and during steady-state exercise at different intensities is very consistent. South African Sports Med J 8(2):8-11, 2001

36.  Lambert EV, Goedecke JH, van Zyl C, Murphy K, Hawley JA, Dennis SC, Noakes TD. High fat diet vs habitual diet prior to carbohydrate loading: Effects on exercise metabolism and cycling performance. Int J Sports Nutr Exerc Metab 11(2):209-225, 2001

37.  Goedecke JH, St Clair Gibson A, Grobler L, Collins M, Noakes TD, Lambert EV. Determinants of the variability in respiratory exchange ratio at rest and during exercise in trained athletes. Am J Physiol Endocrinol Metab 279(6): E1325-E1334, 2000

38.  Goedecke JH, Christie, C; Wilson, G; Dennis, SC; Noakes, TD; Lambert, EV. Metabolic adaptations to a high fat diet in endurance cyclists. Metabolism 48 (12) 1-10, 1999

39.  Goedecke JH, Elmer-English R, Noakes, TD, Dennis SC, Lambert EV. Effects of medium chain triacylglycerol co-ingested with carbohydrate, on exercise metabolism and performance. Int J Sports Nutr 9 (1): 35-47, 1998

40.  Lambert EV, Hawley JA, Goedecke JH, Noakes TD, Dennis SC. Nutritional strategies for promoting fat utilisation and delaying the onset of fatigue during prolonged exercise. J Sports Sciences 15: 315-324, 1997

41.  Bridger RS, Cabion N, Goedecke JH, Rickard S, Schabort EJ, Westgarth-Taylor C, Lambert MI. Physiological evaluation of a shovelling task using a conventional and two-handed shovel. Ergonomics 40(11): 1212-1219, 1997

 

Invited publications:

1.     Goedecke JH, Havemann L.  Fat as fuel during exercise. CME 26(7):347-349, 2008

2.     Lambert EV, Goedecke JH. Editorial: Weight control. CME 23(11):537, 2005

3.     Goedecke JH, Jennings C. Ethnic differences in obesity. CME 23(11):546-550, 2005

4.     Lambert EV, Goedecke JH. You are what you eat? CME 23(11):571-575, 2005

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